P46S (p.Pro46Ser) variant of DYRK1A (Q13627)
P46S (p.Pro46Ser) in DYRK1A (Q13627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
P46S (p.Pro46Ser) variant details
- p.Pro46Ser
- gnomAD 21-37472809-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.587
- MetaLR 0.12
- MetaSVM -1.04
- CADD 23.30
- PolyPhen-2 0.04
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available