P35L (p.Pro35Leu) variant of DYRK1A (Q13627)
P35L (p.Pro35Leu) in DYRK1A (Q13627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
P35L (p.Pro35Leu) variant details
- p.Pro35Leu
- cosmic curated COSV10735
- gnomAD rs1471802278
- Missense
- Variant Prioritization Score for Impact Estimate 0.597
- MetaLR 0.17
- MetaSVM -0.91
- CADD 23.60
- PolyPhen-2 0.12
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available