K11T (p.Lys11Thr) variant of DYRK1A (Q13627)
K11T (p.Lys11Thr) in DYRK1A (Q13627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
K11T (p.Lys11Thr) variant details
- p.Lys11Thr
- gnomAD 21-37472705-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- MetaLR 0.32
- MetaSVM -0.44
- CADD 28.00
- PolyPhen-2 0.97
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 4.6e-05)
- Structural context available
- Literature evidence available