K11R (p.Lys11Arg) variant of DYRK1A (Q13627)
K11R (p.Lys11Arg) in DYRK1A (Q13627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
K11R (p.Lys11Arg) variant details
- p.Lys11Arg
- gnomAD 21-37472705-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.489
- MetaLR 0.32
- MetaSVM -0.45
- CADD 27.20
- PolyPhen-2 0.95
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available