G32R (p.Gly32Arg) variant of DYRK1A (Q13627)
G32R (p.Gly32Arg) in DYRK1A (Q13627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
G32R (p.Gly32Arg) variant details
- p.Gly32Arg
- gnomAD rs1447082182
- Missense
- Variant Prioritization Score for Impact Estimate 0.614
- MetaLR 0.18
- MetaSVM -0.84
- CADD 25.60
- PolyPhen-2 0.53
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available