G27S (p.Gly27Ser) variant of DYRK1A (Q13627)
G27S (p.Gly27Ser) in DYRK1A (Q13627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
G27S (p.Gly27Ser) variant details
- p.Gly27Ser
- ExAC rs769445831
- gnomAD rs769445831
- Missense
- Variant Prioritization Score for Impact Estimate 0.644
- MetaLR 0.33
- MetaSVM -0.63
- CADD 25.20
- PolyPhen-2 0.99
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available