A25T (p.Ala25Thr) variant of DYRK1A (Q13627)
A25T (p.Ala25Thr) in DYRK1A (Q13627) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
A25T (p.Ala25Thr) variant details
- p.Ala25Thr
- gnomAD 21-37472746-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- MetaLR 0.13
- MetaSVM -1.04
- CADD 24.20
- PolyPhen-2 0.01
- SIFT 0.18
- Population evidence available
- Structural context available
- Literature evidence available