V61I (p.Val61Ile) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
V61I (p.Val61Ile) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
V61I (p.Val61Ile) variant details
- p.Val61Ile
- gnomAD rs1180404140
- Missense
- Variant Prioritization Score for Impact Estimate 0.583
- MetaLR 0.13
- MetaSVM -0.83
- CADD 22.00
- PolyPhen-2 0.32
- SIFT 0.10
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available