V60M (p.Val60Met) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
V60M (p.Val60Met) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
V60M (p.Val60Met) variant details
- p.Val60Met
- Ensembl rs1566011799
- Missense
- Variant Prioritization Score for Impact Estimate 0.653
- MetaLR 0.38
- MetaSVM -0.09
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-06)
- Structural context available