V25M (p.Val25Met) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
V25M (p.Val25Met) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
V25M (p.Val25Met) variant details
- p.Val25Met
- gnomAD rs2044643460
- Missense
- Variant Prioritization Score for Impact Estimate 0.648
- MetaLR 0.29
- MetaSVM -0.39
- CADD 29.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available