S59Y (p.Ser59Tyr) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
S59Y (p.Ser59Tyr) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
S59Y (p.Ser59Tyr) variant details
- p.Ser59Tyr
- gnomAD 12-113058368-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.553
- MetaLR 0.22
- MetaSVM -0.84
- CADD 24.60
- PolyPhen-2 0.77
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available