S59A (p.Ser59Ala) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
S59A (p.Ser59Ala) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
S59A (p.Ser59Ala) variant details
- p.Ser59Ala
- 1000Genomes rs1592839246
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- MetaLR 0.13
- MetaSVM -0.90
- CADD 23.30
- SIFT 0.02
- Most common in the 1KG:PJL population (allele frequency 0.0052)
- Structural context available