S35G (p.Ser35Gly) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
S35G (p.Ser35Gly) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
S35G (p.Ser35Gly) variant details
- p.Ser35Gly
- gnomAD 12-113058295-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- MetaLR 0.02
- MetaSVM -1.00
- CADD 20.90
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available