N21T (p.Asn21Thr) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
N21T (p.Asn21Thr) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
N21T (p.Asn21Thr) variant details
- p.Asn21Thr
- TOPMed rs1009981596
- gnomAD rs1009981596
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- MetaLR 0.03
- MetaSVM -1.08
- CADD 23.60
- PolyPhen-2 0.10
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available