M10T (p.Met10Thr) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
M10T (p.Met10Thr) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
M10T (p.Met10Thr) variant details
- p.Met10Thr
- 1000Genomes rs200824699
- ExAC rs200824699
- TOPMed rs200824699
- gnomAD rs200824699
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- MetaLR 0.02
- MetaSVM -1.00
- CADD 22.90
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the 1KG:CHB population (allele frequency 0.0049)
- Structural context available