M10L (p.Met10Leu) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
M10L (p.Met10Leu) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
M10L (p.Met10Leu) variant details
- p.Met10Leu
- TOPMed rs1298847491
- gnomAD rs1298847491
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- MetaLR 0.01
- MetaSVM -0.95
- CADD 4.07
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available