H6Y (p.His6Tyr) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
H6Y (p.His6Tyr) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
H6Y (p.His6Tyr) variant details
- p.His6Tyr
- ESP rs373827220
- gnomAD rs373827220
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- MetaLR 0.02
- MetaSVM -1.02
- CADD 17.60
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available