H34Y (p.His34Tyr) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
H34Y (p.His34Tyr) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
H34Y (p.His34Tyr) variant details
- p.His34Tyr
- gnomAD rs1241663277
- Missense
- Variant Prioritization Score for Impact Estimate 0.467
- MetaLR 0.08
- MetaSVM -1.03
- CADD 16.20
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available