G58V (p.Gly58Val) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
G58V (p.Gly58Val) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
G58V (p.Gly58Val) variant details
- p.Gly58Val
- gnomAD rs1456848938
- Missense
- Variant Prioritization Score for Impact Estimate 0.644
- MetaLR 0.29
- MetaSVM -0.45
- CADD 26.80
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available