G58D (p.Gly58Asp) variant of DTX1 (E3 ubiquitin-protein ligase DTX1)
G58D (p.Gly58Asp) in DTX1 (E3 ubiquitin-protein ligase DTX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
G58D (p.Gly58Asp) variant details
- p.Gly58Asp
- gnomAD rs1456848938
- Missense
- Variant Prioritization Score for Impact Estimate 0.627
- MetaLR 0.19
- MetaSVM -0.86
- CADD 26.70
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available