V35M (p.Val35Met) variant of DSC2 (Desmocollin-2)
V35M (p.Val35Met) in DSC2 (Desmocollin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
V35M (p.Val35Met) variant details
- p.Val35Met
- TOPMed rs1987673089
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.26
- CADD 15.20
- PolyPhen-2 0.99
- SIFT 0.06
- Population evidence available
- Structural context available