T6S (p.Thr6Ser) variant of DRD4 (D(4) dopamine receptor)
T6S (p.Thr6Ser) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
T6S (p.Thr6Ser) variant details
- p.Thr6Ser
- TOPMed rs1799989297
- gnomAD rs1799989297
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.13
- AlphaMissense 0.07
- MetaLR 0.12
- MetaSVM -0.90
- CADD 9.66
- PolyPhen-2 0.06
- Most common in the REMAINING population (allele frequency 2.3e-05)
- Structural context available