S5N (p.Ser5Asn) variant of DRD4 (D(4) dopamine receptor)
S5N (p.Ser5Asn) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S5N (p.Ser5Asn) variant details
- p.Ser5Asn
- TOPMed rs1391713906
- gnomAD rs1391713906
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.11
- AlphaMissense 0.15
- MetaLR 0.17
- MetaSVM -0.94
- CADD 11.70
- PolyPhen-2 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available