S5I (p.Ser5Ile) variant of DRD4 (D(4) dopamine receptor)
S5I (p.Ser5Ile) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
S5I (p.Ser5Ile) variant details
- p.Ser5Ile
- gnomAD 11-637318-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.17
- MetaLR 0.20
- MetaSVM -0.92
- CADD 17.90
- PolyPhen-2 0.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available