S5G (p.Ser5Gly) variant of DRD4 (D(4) dopamine receptor)
S5G (p.Ser5Gly) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
S5G (p.Ser5Gly) variant details
- p.Ser5Gly
- TOPMed rs1404914278
- gnomAD rs1404914278
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.16
- AlphaMissense 0.08
- MetaLR 0.19
- MetaSVM -0.94
- CADD 16.30
- PolyPhen-2 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available