S27Y (p.Ser27Tyr) variant of DRD4 (D(4) dopamine receptor)
S27Y (p.Ser27Tyr) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
S27Y (p.Ser27Tyr) variant details
- p.Ser27Tyr
- gnomAD 11-637384-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.12
- MetaLR 0.15
- MetaSVM -0.89
- CADD 14.50
- PolyPhen-2 0.10
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available