S27T (p.Ser27Thr) variant of DRD4 (D(4) dopamine receptor)
S27T (p.Ser27Thr) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
S27T (p.Ser27Thr) variant details
- p.Ser27Thr
- gnomAD rs1858083847
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.06
- AlphaMissense 0.08
- MetaLR 0.13
- MetaSVM -1.05
- CADD 0.62
- PolyPhen-2 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available