S27G (p.Ser27Gly) variant of DRD4 (D(4) dopamine receptor)
S27G (p.Ser27Gly) in DRD4 (D(4) dopamine receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
S27G (p.Ser27Gly) variant details
- p.Ser27Gly
- rs869141319
- gnomAD 11-637376-GGGGGCA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.297
- CADD 19.90
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- Literature evidence available