S23Y (p.Ser23Tyr) variant of DRD4 (D(4) dopamine receptor)
S23Y (p.Ser23Tyr) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
S23Y (p.Ser23Tyr) variant details
- p.Ser23Tyr
- gnomAD 11-637372-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.20
- MetaLR 0.16
- MetaSVM -0.95
- CADD 14.50
- PolyPhen-2 0.01
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available