S23L (p.Ser23Leu) variant of DRD4 (D(4) dopamine receptor)
S23L (p.Ser23Leu) in DRD4 (D(4) dopamine receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
S23L (p.Ser23Leu) variant details
- p.Ser23Leu
- rs1382058392
- gnomAD 11-637371-TC-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.593
- CADD 16.40
- Most common in the African/African-American population (allele frequency 2.6e-05)
- Structural context available
- Literature evidence available