S23F (p.Ser23Phe) variant of DRD4 (D(4) dopamine receptor)
S23F (p.Ser23Phe) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
S23F (p.Ser23Phe) variant details
- p.Ser23Phe
- TOPMed rs1408168512
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.13
- AlphaMissense 0.17
- MetaLR 0.17
- MetaSVM -0.99
- CADD 15.70
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.7e-05)
- Structural context available