R4L (p.Arg4Leu) variant of DRD4 (D(4) dopamine receptor)
R4L (p.Arg4Leu) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R4L (p.Arg4Leu) variant details
- p.Arg4Leu
- Ensembl rs1321681323
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.09
- AlphaMissense 0.12
- MetaLR 0.14
- MetaSVM -1.02
- CADD 21.80
- PolyPhen-2 0.07
- Population evidence available
- Structural context available