R4H (p.Arg4His) variant of DRD4 (D(4) dopamine receptor)
R4H (p.Arg4His) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
R4H (p.Arg4His) variant details
- p.Arg4His
- gnomAD 11-637315-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.15
- MetaLR 0.15
- MetaSVM -0.93
- CADD 19.00
- PolyPhen-2 0.31
- SIFT 0.22
- Population evidence available
- Structural context available
- Literature evidence available