R16S (p.Arg16Ser) variant of DRD4 (D(4) dopamine receptor)
R16S (p.Arg16Ser) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
R16S (p.Arg16Ser) variant details
- p.Arg16Ser
- gnomAD 11-637350-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.165
- REVEL 0.04
- MetaLR 0.10
- MetaSVM -1.04
- CADD 11.20
- PolyPhen-2 0.03
- SIFT 0.48
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available