R16L (p.Arg16Leu) variant of DRD4 (D(4) dopamine receptor)
R16L (p.Arg16Leu) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
R16L (p.Arg16Leu) variant details
- p.Arg16Leu
- gnomAD 11-637351-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.02
- MetaLR 0.09
- MetaSVM -1.02
- CADD 7.92
- PolyPhen-2 0.03
- SIFT 0.30
- Population evidence available
- Structural context available
- Literature evidence available