P18T (p.Pro18Thr) variant of DRD4 (D(4) dopamine receptor)
P18T (p.Pro18Thr) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
P18T (p.Pro18Thr) variant details
- p.Pro18Thr
- gnomAD 11-637356-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.03
- MetaLR 0.12
- MetaSVM -1.02
- CADD 3.81
- PolyPhen-2 0.00
- SIFT 0.14
- Population evidence available
- Structural context available
- Literature evidence available