P18S (p.Pro18Ser) variant of DRD4 (D(4) dopamine receptor)
P18S (p.Pro18Ser) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P18S (p.Pro18Ser) variant details
- p.Pro18Ser
- TOPMed rs1858081469
- gnomAD rs1858081469
- Missense
- Variant Prioritization Score for Impact Estimate 0.147
- REVEL 0.01
- AlphaMissense 0.07
- MetaLR 0.10
- MetaSVM -1.02
- CADD 2.81
- PolyPhen-2 0.03
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.8e-05)
- Structural context available