P18R (p.Pro18Arg) variant of DRD4 (D(4) dopamine receptor)
P18R (p.Pro18Arg) in DRD4 (D(4) dopamine receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
P18R (p.Pro18Arg) variant details
- p.Pro18Arg
- rs996621902
- gnomAD 11-637352-CG-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.214
- CADD 18.80
- Most common in the African/African-American population (allele frequency 4.9e-05)
- Structural context available
- Literature evidence available