P18A (p.Pro18Ala) variant of DRD4 (D(4) dopamine receptor)
P18A (p.Pro18Ala) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P18A (p.Pro18Ala) variant details
- p.Pro18Ala
- TOPMed rs1858081469
- gnomAD rs1858081469
- Missense
- Variant Prioritization Score for Impact Estimate 0.15
- REVEL 0.03
- AlphaMissense 0.05
- MetaLR 0.10
- MetaSVM -1.02
- CADD 1.36
- PolyPhen-2 0.02
- Most common in the REMAINING population (allele frequency 2.1e-05)
- Structural context available