N3I (p.Asn3Ile) variant of DRD4 (D(4) dopamine receptor)
N3I (p.Asn3Ile) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
N3I (p.Asn3Ile) variant details
- p.Asn3Ile
- Ensembl rs1437241985
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.13
- AlphaMissense 0.32
- MetaLR 0.21
- MetaSVM -0.85
- CADD 21.50
- PolyPhen-2 0.29
- Most common in the 1KG:CHS population (allele frequency 0.0051)
- Structural context available