L13M (p.Leu13Met) variant of DRD4 (D(4) dopamine receptor)
L13M (p.Leu13Met) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
L13M (p.Leu13Met) variant details
- p.Leu13Met
- gnomAD 11-637341-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.09
- MetaLR 0.31
- MetaSVM -0.87
- CADD 17.90
- PolyPhen-2 0.86
- SIFT 0.28
- Population evidence available
- Structural context available
- Literature evidence available