L12M (p.Leu12Met) variant of DRD4 (D(4) dopamine receptor)
L12M (p.Leu12Met) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
L12M (p.Leu12Met) variant details
- p.Leu12Met
- gnomAD 11-637338-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.09
- MetaLR 0.18
- MetaSVM -0.97
- CADD 17.10
- PolyPhen-2 0.05
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available