L12C (p.Leu12Cys) variant of DRD4 (D(4) dopamine receptor)
L12C (p.Leu12Cys) in DRD4 (D(4) dopamine receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
L12C (p.Leu12Cys) variant details
- p.Leu12Cys
- gnomAD 11-637334-CG-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.173
- CADD 13.00
- Population evidence available
- Structural context available
- Literature evidence available