G2W (p.Gly2Trp) variant of DRD4 (D(4) dopamine receptor)
G2W (p.Gly2Trp) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
G2W (p.Gly2Trp) variant details
- p.Gly2Trp
- gnomAD 11-637308-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.433
- REVEL 0.25
- MetaLR 0.48
- MetaSVM -0.78
- CADD 25.10
- PolyPhen-2 0.98
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available