G2R (p.Gly2Arg) variant of DRD4 (D(4) dopamine receptor)
G2R (p.Gly2Arg) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
G2R (p.Gly2Arg) variant details
- p.Gly2Arg
- gnomAD 11-637308-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.391
- REVEL 0.21
- MetaLR 0.28
- MetaSVM -0.85
- CADD 24.20
- PolyPhen-2 0.68
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available