G2E (p.Gly2Glu) variant of DRD4 (D(4) dopamine receptor)
G2E (p.Gly2Glu) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
G2E (p.Gly2Glu) variant details
- p.Gly2Glu
- gnomAD 11-637309-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.11
- MetaLR 0.19
- MetaSVM -0.95
- CADD 15.40
- PolyPhen-2 0.04
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available