G25W (p.Gly25Trp) variant of DRD4 (D(4) dopamine receptor)
G25W (p.Gly25Trp) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
G25W (p.Gly25Trp) variant details
- p.Gly25Trp
- gnomAD 11-637377-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.12
- MetaLR 0.23
- MetaSVM -0.86
- CADD 20.30
- PolyPhen-2 0.71
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available