G25E (p.Gly25Glu) variant of DRD4 (D(4) dopamine receptor)
G25E (p.Gly25Glu) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G25E (p.Gly25Glu) variant details
- p.Gly25Glu
- TOPMed rs1248931429
- gnomAD rs1248931429
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.04
- AlphaMissense 0.11
- MetaLR 0.11
- MetaSVM -1.03
- CADD 5.30
- PolyPhen-2 0.00
- Most common in the South Asian population (allele frequency 1.9e-05)
- Structural context available