G21W (p.Gly21Trp) variant of DRD4 (D(4) dopamine receptor)
G21W (p.Gly21Trp) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
G21W (p.Gly21Trp) variant details
- p.Gly21Trp
- gnomAD 11-637365-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.16
- MetaLR 0.42
- MetaSVM -0.84
- CADD 22.80
- PolyPhen-2 0.96
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available