G21V (p.Gly21Val) variant of DRD4 (D(4) dopamine receptor)
G21V (p.Gly21Val) in DRD4 (D(4) dopamine receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G21V (p.Gly21Val) variant details
- p.Gly21Val
- TOPMed rs1031335519
- gnomAD rs1031335519
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.14
- AlphaMissense 0.10
- MetaLR 0.27
- MetaSVM -0.90
- CADD 7.00
- PolyPhen-2 0.80
- Most common in the African/African-American population (allele frequency 5.2e-05)
- Structural context available